A Roman by birth, Felix was chosen as Pope on 5 January 269, in succession to Pope Dionysius, who had died on 26 December 268.
Felix was the author of an important dogmatic letter on the unity of Christ's Person. The notice about Felix in the Liber Pontificalis ascribes to him a decree that Masses should be celebrated on the tombs of martyrs ("Hic constituit supra memorias martyrum...